Start by checking that pages and interactions work
If you do not need a specific region, start with an available route in a region you use often. Visit sites you use regularly and check that images, sign-ins, search, and file loading work. A page appearing does not mean every resource has loaded. If text appears but images keep loading, first check your split-tunneling settings and the routes used to access the relevant resource domains.
Keep the route that works smoothly for everyday use; there is no need to switch frequently over brief differences in feel. If only one site has a problem while other services work, check whether the site needs you to sign in again or is experiencing an issue, then compare other routes in the same region.